Tuesday, April 13, 2010

Embryo Grading and IVF Timetable

You can ask the Lab Director (or physician) to give you progress reports on the development of your embryos. Critical points in development are (1) fertilization, (2) 4 to 8 cell stage and (3) morula to blastocyst stage.

Numeric grading systems for multicell embryos usually have 4 levels:

Grade 1: even cell division, no fragmentation
Grade 2: even cell division, small fragmentation
Grade 3: uneven cell division, moderate fragmentation
Grade 4: uneven cell division, excessive fragmentatio

The following is an approximate timetable of events for IVF:

Day 0 Egg retrieval Sperm collection and preparation Insemination
Day 1 Check eggs for fertilization (the presence of two pronuclei or PN's)
Day 2 Embryos at the 4-cell or more stage of development
Day 3 Embryos at the 8-cell or more stage of development
Day 4 Embryos at the compacted morula (16-32 cell) stage
Day 5 Embryos at the blastocyst stage of developmen

The number refers to the degree of expansion of the blastocyst (1 is the least expanded, 6 is the most expanded). The first letter (A,B, or C) refers to the quality of the inner cell mass (the part of the blastocyst that is going to be the baby) and the second letter (A, B, or C) refers to the quality of the trophectoderm (the part of the blastocyst that is going to be the placenta).

Multicell embryos that recieve grade 1 or 2 often develop to the blastocyst stage, those receiving grade 3 or 4 rarely develop to the blastocyst stage. Sometimes the laboratory uses the reversed scale where a grade 4 embryo is equivalent to a grade 1 embryo on the above scale. Please Check with your lab.

Wednesday, April 7, 2010

Career women avoding sex

Many women turn to IVF too quickly. Now these days career women are avoiding sex and seeking inappropriate IVF treatment to have instant babies, doctors have claimed. It is estimated that one in seven couples have difficulty conceiving. However, many women take up IVF treatment, before they discover this because they are simply too busy or tired to have sex.

Just like technology,now couples think IVF a technology to have easy baby. India being bit conservative, ratio of these cases are high in developed counteries. Although IVF treatment costs from 1 to 1.5 Lac in India for just one typical cycle, and chances of success in First IVF cycle are less, still people opt for IVF.

The chances of conceiving of a woman under 35 with IVF is around one third. A woman the same age who has sex regularly for a month has a one in four chance of conception. However Delhi IVF discourage women from seeking treatment if they have not tried to conceive naturally. We always there for treatment for people who are unable to have baby naturally.

IVF also do not hold good results above 38 or 40 year of age. Male factor also there for OLD age couples. So even if you delay in family by choice chances to have babay by naturally or by IVF are alwasy less.