Reasons to have IVF treatment at Delhi -IVF

There are many IVF clinic coming up every day in India and its very hard for patients to choose right Doctor and Clinic. Many time they ask why DELHI IVF.

My Reply to this is "EXPERIANCE COUNTS more then the DECOR"

The clinic started in 1994 by Dr. Indra Hinduja Pioneer of IVF in India.

Yes many of patients realy seek information about:

Size of Clinic : We have good size clinic with required facilities. Even a Big Hospital has same size of Facility or less then this for IVF alone.

BedSize and Cleaning : As we usnerstand that IVF need most clean anvironment to avoide any infection or problem. So we take care of this at TOP level.

Clinical skills: Our Records and experiance tell you this. We are the Oldest and with best results ever.

Reputation, Trust and transparency: As we are Oldest In delhi, people trust us and we have proven track record to justify the same.

We also have:

• Psychological counseling - This help to Half the battle to won.
• All under one roof facilities. You need not to run for tests and medicines.
• State fo art latest equipments and technology.
• Personal Care, emotional touch of staff members.
• Best located and We are centrally located and surrounded with many of tourist places.
• We have high success rate and rated top IVF clinics in India.
• 14 year of experience.
• We take extra care for hygiene, cleanliness- DO NOT worry about HIV & other acquired infections.
• We work ourselves and your treatment will be done by the same doctor at all stages so he/she understand you better.

A shoulder to cry on - If you fail or have fear.

Delhi IVF and Fertility Research Centre in Delhi India is a super-specialty center, under one roof, devoted solely to the management of childlessness. The Clinic offers economic services conforming to world class standards. It is also catering to patients from around the world.

The facility compares well with the best available centre anywhere in the world, in terms of both equipment and personnel.

No effort is spared at the clinic to identify the specific cause of infertility in each case and to overcome it. After group consultation, treatment is advised and followed through. Diagnosis and treatment at the clinic are both based on sound scientific principle's with close attention paid to the individual requirements of the couples.

Above all what is more important is the END RESULT which is priceless.

Growing Need Of IVF!!!

The number of IVF procedures performed in Australia and New Zealand has almost doubled in the four years between 2004 and 2008 and Still growing.

In India also the need of IVF treatment is increasing due to urbanization and some people opt it for quick solution. The number of babies born following ART treatments is also on the up, growing by great per cent between 2008 and 2010.

In some places like UK, Australia it is due to a voluntary shift in practice by clinicians and patients to single embryo transfer and so some time people go for Multiple IVF treatments. "It is significant because multiple births can result in increased health risks to both mothers and babies."

In India till now there is no law to bind doctors for number of ET. But as a good doctor normally it is not more then 2. Only in case of very low response in first IVF cycle, they might choose 3.

Another reason for growing IVF treatment Specially in India is cost. Due to low cost good IVF clinics like DELHI IVF by DR. Anoop Gupta, with state of art facilities and proven track record.

Another reason can be that many people take IVF as Medical tourism option also. So that way they can go on vacation along with best treatment options.

Fear Of IVF

BIRTH defects caused by in-vitro fertilisation are up to twice as common as previously thought, according to international researchers.

IVF Babies Have Problems or They are Damaged. Contrary to popular belief, IVF babies are born just as healthy as babies conceived naturally. Many people buy into the IVF myth that babies created in a laboratory will be in some way defective. However, in the decades that IVF has been practiced this theory has never been proven true.

Fear of wight gain/loss. The chance of having a baby through IVF is risky. According to the American Society for Reproductive Medicine (ASRM), the average live delivery rate for IVF in 2007 was 39.9 percent per retrieval. And there is no risk

This is an exclusive quality of Delhi-IVF staff and doctors. We literally work like a family here right from Dr. Anoop Gupta to his wife Mrs. Alka Gupta (Embryologist) Dr. Deeksha Tyagi, sister Jancy, Marriamma, Virgin, Jomol, Darsana, Pawan and Mrs. Kalra. Whom so ever you meet and get a IVF done, they will remember you by your first name.

By chance you do not succeed in your first attempt, they will all be there by your side to give you a moral and emotional support and boost you further for the next cycle. You yourself will become a part of our family at DIFC.

We have full service and treatment for Infertility and provide care at every level. We understand the emotional need of infertile couples.

FAQ to Preimplantation Genetic Diagnos Performed (PGD)

Who would be benefited by PGD?

Couples with a history of recurrent miscarriage.
Women with history of repeated IVF failures
Family history of with genetic abnormality like beta thalassemai
previously affected child with genetic abnormailty like downs syndrome
known carriers of genetic defects like chromosome translocations.
women who have had to undergo repeated terminations because od an abnormality diagnosed prenatal.
couples morally and religiously opposed to termination of affected pregnancies diagnosed prenatal.

In couples with severe male factor infertility.


How is PGD diff from other prenatal diagnostic techniques?
There are various prenantal diagnostic techniques which presently help in the detection of certain genetic disorders in the fetus. These includes :
1- Chronic Villus biopsy (doen at 10-12 weeks of gestation)
2- Amniocentesis (done at 16-18 weeks if gestation)
Cordocentesis (done at 20-22 weeks of gestation)

The main genetic disorders tested include

1- cytogenetic anomalies i.e structural & numerical chromosomal abnormalities - diagnosed by karyotyping or FISH
2- Molecular genetic disrders i.e single gene disorders - diagnosed by PCR

As opposed to these prenetal diagnostic techniques, in PGD, the diagnostic techniques like FISH & PCR can be performed on the blastomere obtained from the embryo prior to implantaion. PGD thus helps to obviote the physical, emotional & psychological trauma assosiated with termination of pregnancy.

What is FISH?
FISH is molecular cytogenesis technique, which can be performed in non-dividing inter phase cells. FISH involves a chromosome specific fluorescently labeled DNA probes to hybridize to complementary genomic DNA. the signals are visualized using a fluorescene microscope. In case of normal diploid cell. tow signals are send for each chromosome. Presence of one signal for the chromosome being analyzed suggests monosomy and presence of three signals for the chromosome indicated trisome. FISH is rapid, reliable and useful genetic diagnostic test.

Which disorders can be diagnosed by FISH?
FISH can be used for

1- Detection of aneuploidies (numerical abnormalities)
2- Detection of translocations (structural abnormalities)
3- Sexing of the embryo (for x-linked disorders)



In PGD, which chromosomes are usually tested by FISH analysis?
the chromosomes most commonly tested include chromosomes 12, 18, 21, X & Y. The other chromosomes can be tested as and when indicated.

Incase of translocations in either of the parents specific to the patient need to be ordered.


What is PCR?
PCR is a powerful molecular diagnostic technique that allows in vitro amplification of a particular DNA fragmant, allowing generation of millions of copies in a short duration.


Which disorders can be diagnosed by PCR?
PCR is useful in the disgnosis of single gene disorders like beta thalassemia, cystic fibrosos, Ducchenne's muscular dystrophy, etc.

Can PGD be used for sex selection?
PGD can be used for proconception sex selection at the embryonic stage. according to the prenatal diagnostic techniques act, 1994, sexing of embryos is prohibited in India. However sexing of embryos can be performed for medical indications as in case of X linked disorders, where only female embtos (normal or carriers) may be tranfered.

What may be the problems encountered during performing PGD?
- Th case the embryo has started compacting, then it may be difficuilt to perform teh embryo biopsy.
- The cell may be lost during the procedure of embryo biopsy.
- The cell may be lost during fixation of cell on teh slide.
-The FISH signals may not be clear/ overlapping / split in some cases, making the diagnosis difficuilt.
- Mosaicism


Advantages of PGD?
- It is performed at the preimpantation state i.e befire the onset of pregnancy. PGD helps to increase the chances of having a normal baby.
- PGD helps to increase teh pregnancy rate and decrease the miscarriage rate.

How Preimplantation Genetic Diagnose (PGD) is done

How Preimplantation Genetic Diagnos Performed (PGD)


For PGD enbryos need to be generated in vitro. It must go through the ICSI procedure. The embryo are cultured in viro,byopsy is performed on the third day of fertilization and bad cells are removed from embryo. The biopsied cell is subjected to genetic diagnostic testes like FISH or Polymerase Chain Reaction (PCR). The results of genetic analysis are avialable in 12-36 Hrs. Once the results of the genetic analysis are obtained the enbryo which are normal are then trafsfred back to have the healthy baby.

Basic steps of the PGD are:

• Down Regulation
• Ovarian stimulation
• Oocyte Retrieval
• ICSI
• Embryo Culture
• Embryo Biopsy
• Genetic analysis (FISH or PCR)
• Embryo Transfer

How is embyo biopsy performed?

Cleavage stage embryo:
1- A hole drilled in the zona using laser or acid triodes
2- aspiration pipette broght close to the blastomere to be aspirated
3- the blastomere is aspirated with gentle suction
4- single blastomere with the nucleus clearly visible which is subjected to FISH or PCR.